Age-related Changes in Posture Control and Cortex Activity Under a Dynamic Perturbation

Completed

• Conditions: Aging

• Registration Number: NCT02706496
• Lead Sponsor: Taipei Veterans General Hospital, Taiwan

Brief Summary

With aging, the elderly decreased ability to control postural balance will be accompanied by increased risk of falling (Berg et al, 1992;. Tinetti et al, 1988). According to previous studies, it showed that the elderly over 65 years fall each year probability was 30 %, and it increased with age (Skelton, \& Todd, 2004). In view of this, age-related posture control has become important issues of modern preventive medicine and family care.

Detailed Description

Many clinical studies have been developed assessment tools and measurements for clinical staff to provide balanced assessment and intervention. However, the factors of affecting postural control are diverse and complex, not all tools or measurement could effectively detect a risk of falling. In daily living, the postural control involved integration of sensation, biofeedback, movement response, and kinesthetic sense to maintain postural stability, and finally integrated into the neuromuscular system and coordination to help achieve the perfect postural control. Current clinical tools used to assess the fall or research methods to detect the incidence of falls and the lack of effective relevant and contradictory, and it's difficult to effectively evaluate the risk of falls (Gates, et al, 2008).

With the development of postural balance issues associated with aging process in older people, there is no set of standardized equipment, and lack of effective methods for the assessment of normal and older people who fall. In response to these problems, if we can provide a virtual reality interfaces, and with daily living activities as gait, across obstacles activity, sit to stand, will be able to better meet the desire to explore the issue of real significance to enhance researchers for aging, motion analysis, and brain cortex activity mechanism in postural control mechanism.

Study Timeline

• Study Start: 2015-02
• Primary Completion: 2015-08
• Study First Submitted: 2015-08-25
• Study Completion: 2016-01
• Status Verified: 2016-03
• Study First Submitted QC: 2016-03-07
• Last Update Submitted: 2016-03-07
• Study First Posted: 2016-03-11
• Last Update Posted: 2016-03-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 37

Inclusion Criteria

• able to walk and climb the stairs without assistive devices,
• could follow the instructions, and
• without well-known balance related diseases or impairments.

Exclusion Criteria

• With the disease of cardiac and pulmonary system, neuromusculoskeletal system, vision, vestibular apparatus, dizziness experience or cognitive deficit would be excluded the study.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
center of pressure	3 minutes for 20 trial	0.5m pressure mat (RSscan, Inc., Belgium)

Secondary Outcome Measures

Name	Time	Method
cortex power spectrum density	3 minutes for 20 trial	32-channel Ag/AgCl Quick-Cap and NuAmps digital amplifier (Neuroscan, El Paso, TX, USA)

Trial Locations

Locations (1)

Taipei Veterans General Hospital; 🇨🇳 Taipei, Taiwan