Mapping Mood in the Subthalamic Nucleus in Parkinson's Disease (PD)
Completed
- Conditions
- Parkinson's DiseaseDepressionAnxiety
- Registration Number
- NCT00847431
- Lead Sponsor
- Washington University School of Medicine
- Brief Summary
The goal of this study is to determine the vulnerability of mood-related neurocircuitry in Parkinson Disease (PD) using deep brain stimulation of the subthalamic nucleus (STN DBS).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 81
Inclusion Criteria
Not provided
Exclusion Criteria
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie mood changes in Parkinson's disease patients undergoing STN DBS?
How does STN DBS compare to standard-of-care treatments for depression and anxiety in PD patients?
What biomarkers are associated with mood response prediction in subthalamic nucleus stimulation for PD?
What adverse events are reported with STN DBS for mood modulation in Parkinson's disease?
Are there combination therapies or alternative targets to STN DBS for managing PD-related depression and anxiety?
Trial Locations
- Locations (2)
Washington University School of Medicine
🇺🇸St. Louis, Missouri, United States
University of Cincinnati, Movement Disorder Center
🇺🇸Cincinnati, Ohio, United States
Washington University School of Medicine🇺🇸St. Louis, Missouri, United States