Transversus Thoracic Plane Block for Perioperative Analgesia in Cardiac Surgery
- Conditions
- Cardiac SurgeryPost Operative PainTransversus Thoracic Plane Block
- Interventions
- Procedure: Transversus Thoracic Plane Block
- Registration Number
- NCT06546722
- Lead Sponsor
- Saint-Joseph University
- Brief Summary
The goal of this clinical trial is to learn if perioperative Transversus Thoracic Plane Block (TTPB) decrease perioperative pain after cardiac surgery. The main questions it aims to answer are:
1. does Transversus Thoracic Plane Block decrease perioperative pain after cardiac surgery more than the standard analgesic treatment?
2. Are the results different if the investigators perform Transversus Thoracic Plane Block before surgery or at the end of surgery?
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 150
- All patients scheduled for cardiac surgery via sternotomy under cardiopulmonary bypass
- Previous cardiac surgery
- Urgent surgery
- Pregnant women
- Allergy to local anesthetics
- Opioid dependence
- Low ejection fraction < 30%
- Presence or onset of cognitive or neurological disorders preventing pain assessment
- Infection at injection sites
- Coagulopathy
- Patients on dual antiplatelet therapy
- Renal insufficiency with Glomerular filtration rate (GFR) < 30 mL/min
- History of thoracic radiotherapy
- History of mastectomy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Transversus Thoracic Plane Block post Transversus Thoracic Plane Block This group receives standard analgesic treatment and Transversus Thoracic Plane Block is performed at the end of surgery Transversus Thoracic Plane Block pre Transversus Thoracic Plane Block This group receives standard analgesic treatment and Transversus Thoracic Plane Block is performed before surgery
- Primary Outcome Measures
Name Time Method postoperative pain score First 24h postoperatively The primary outcome is Postoperative Pain Score:
Numeric rating scale (NRS) ratings will be assessed at T1 (= upon patient awakening), T2 (= 12 hours postoperatively), T3 (= 24 hours postoperatively) as well as during various painful moments (coughing, drain removal, mobilization).
Numeric rating scale (NRS) is a unidimensional measure of pain intensity. It consists of the patient evaluating his pain out of a series of numbers ranging from 0 to 10, where the 2 respective endpoints are "0 = no pain" and "10 = worst possible pain."
- Secondary Outcome Measures
Name Time Method Time to first opioid administration First 24h postoperatively Time to first opioid administration after surgery
Incidence of postoperative pneumonia and pneumothorax in cardiac intensive care unit First 24h postoperatively Incidence of postoperative pneumonia and pneumothorax in cardiac intensive care unit
Perioperative opioid requirement First 24h postoperatively Total dose of opioids required during surgery and 24h postoperatively
Length of stay at cardiac intensive care unit and hospital stay 3 months postoperatively Length of stay at cardiac intensive care unit and hospital stay
Time to extubation First 24h postoperatively Time between arrival to cardiac intensive care unit and extubation
Patient satisfaction at 24 hours post surgery First 24h postoperatively Patient satisfaction is measured by asking patients one question at 24 hours post surgery:
"On a scale from 0 to 10, 0 = not satisfied at all, 10 = extremely satisfied, how satisfied do you feel concerning pain management during the first 24 hours after surgery? "
Trial Locations
- Locations (1)
Hotel Dieu de France
🇱🇧Beirut, Lebanon