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Efficacy of green tea extract in the treatment of the patients with dry eye.

Phase 2
Conditions
Dry eye.
Diseases of the eye and adnexa
Registration Number
IRCT2014042117374N1
Lead Sponsor
Shiraz University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
60
Inclusion Criteria

Incliusion criteria included? Dry eye and meibomian gland dysfunction.
Exclusion criteria included? Use of oral tetracyclines and corticosteroids in 3 months before study and all ophthalmic medication in one month before, Patients with other ocular surface disorders such as corneal surface damage, eyelid complications except blepharitis, any previous ocular surgery, history of drug allergy in eye , use of ophthalmic medication to treat other ophthalmic complication except dry eye and blepharitis, severe belepharitis and dry eye that require systemic treatment, Nasolacrimal duct system disorders such as punctal occlusion, Pregnancy and lactation, as well as patients taking systemic medications and systemic diseases affecting this study are excluded.

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Clinical symptom. Timepoint: Before the intervention, one month after the intervention. Method of measurement: The questionnaire included: symptoms of itching, Burning, Reduced vision, Foreign body sensation, Pains, photophobia, Redness.;Tear production. Timepoint: Before the intervention, one month after the intervention. Method of measurement: Shirmer test.;Tear film stability. Timepoint: Before the intervention, one month after the intervention. Method of measurement: Tear Film Brake Up Time test.;Ocular surface health. Timepoint: Before the intervention, one month after the intervention. Method of measurement: Staining of the cornea and conjunctiva.;Meibomian glangd safety. Timepoint: Before the intervention, one month after the intervention. Method of measurement: Color and quality of gland secretion.
Secondary Outcome Measures
NameTimeMethod
Drug allergy. Timepoint: Before the intervention, one month after the intervention. Method of measurement: Clinical symptom.;Eye infection. Timepoint: Before the intervention, one month after the intervention. Method of measurement: Clinical symptom.
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