se Of Local Application Of Tranexamic Acid With Microneedling In Patients Of Melasma
Not Applicable
Completed
- Conditions
- Health Condition 1: null- melasma
- Registration Number
- CTRI/2018/06/014469
- Lead Sponsor
- Government medical college and hospital Chandigarh
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
1.Patients with clinical diagnosis of melasma.
Exclusion Criteria
1.Patients suffering from any significant systemic illness.
2.Patient with known hypersensitivity to tranexamic acid.
3.Patients with any other facial dermatoses.
4. Patients on anticoagulants, oral contraceptive pills, hormone replacement therapy, NSAIDs, antiepileptic medications, isotretinoin or any other phototoxic medication.
5. Pregnancy and lactation.
6. History of thrombotic disease like DVT.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method percentage reduction in Modified MASI (Melasma Area Severity Index) of each half of the face, respose as follow:- <br/ ><br>No response <br/ ><br>Minimal or poor response- 0-25% reduction in the modified MASI score <br/ ><br> Partial or fair response- 26%-50% reduction in the modified MASI score <br/ ><br>Good response- 51-75% reduction in the modified MASI score <br/ ><br>Excellent- 75% reduction in the modified MASI score <br/ ><br>Timepoint: at baseline,2,4 and 8 weeks
- Secondary Outcome Measures
Name Time Method patient satisfaction score as follows;- <br/ ><br>excellent-81-100% <br/ ><br>very good- 61-80% <br/ ><br>good- 41-60% <br/ ><br>fair- 21-40% <br/ ><br>poor-0-20%Timepoint: at baseline,2,4,6 and 8 weeks