The effectiveness of topical tranexamic acid compare to injection into the clamp drain on the bleeding after knee arthroplasty surgery
Phase 3
- Conditions
- Arthrosis of Knee.Primary gonarthrosis, bilateral
- Registration Number
- IRCT2016122730123N1
- Lead Sponsor
- Shahid Sadoughi University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 75
Inclusion Criteria
Inclusion criteria : Adults age between 18- 85 years; patients who need artheroplasty
Exclusion criteria: Secondary artheritis like rheumatoid artheritis; traumatic artheritis; gout; infectious artheritis ; patients with chronic disease (ischemic cardiopathy, nocturnal apnea syndrome, severe pulmonary disease, chronic renal failure, liver failure, and ...; History of thromboembolic disease (platelet under 150000 in milimiter, INR upper 1.4, and PTT 1.4 upper than normal ratio; hemorrhagic disease; allergy to tranxamic acid; anticoagulant drug users
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hemoglobin level of blood. Timepoint: 12 and 48 hour after surgery. Method of measurement: Grams of hemoglobin per deciliter blood with full automatic laboraty devices.
- Secondary Outcome Measures
Name Time Method Deep vein thrombosis. Timepoint: During the hospitalization of patients and during post operational follow up of pateints. Method of measurement: Physical examination and medical history of pateint.