Efficacy and safety study of Topical tranexamic acid to decrease postoperative blood loss in total knee arthroplasty
Not Applicable
Recruiting
- Conditions
- Diseases of the musculo-skeletal system and connective tissue
- Registration Number
- KCT0004298
- Lead Sponsor
- Seoul National University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 325
Inclusion Criteria
Patients who were suffering from knee osteoarthritis and were scheduled to undergo total knee arthroplasty
Exclusion Criteria
acquired disturbances of color vision,
preoperative anemia (a hemoglobin level of <11 g/dL in females and <12 g/dL in males),
coagulopathy (as identified by a preoperative platelet count of <150,000/mm3, international normalized ratio of >1.4, or prolonged partial thromboplastin time [>1.4 times normal]),
history of arterial or venous thromboembolic disease (such as a cerebrovascular accident, deep-vein thrombosis, or pulmonary embolus),
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method decrease in postoperative hemoglobin level
- Secondary Outcome Measures
Name Time Method blood loss calculated using Good's method,;drainage volume;frequency of transfusion