Investigating the effect of topical tranexamic acid on burn wounds
Phase 3
Recruiting
- Conditions
- Burn wound.
- Registration Number
- IRCT20240228061125N1
- Lead Sponsor
- Karaj University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
patients between 15-55 years old over than 20 percent surface of body
need skin debridement
Exclusion Criteria
dont need icu care
not to be third grade burn
dont have chemical or electrical burn
dont have blunt abdominal trauma or head trauma
dont have bleeding disorders
dont have thrombotic disorders or hypercoagulopathy
dont be post partum or pregnant
Hypersensitivity to tranexamic acid
Systolic blood pressure higher than 200 mmHg
Disruption of coagulation factors
Have disturbances in kidney function tests
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hemoglobin level. Timepoint: Complete blood count test before operation and 24 hours after operation. Method of measurement: Complete blood count test through the patient's blood sample.;Hematocrit level. Timepoint: Complete blood count test before operation and 24 hours after operation. Method of measurement: Complete blood count test through the patient's blood sample.
- Secondary Outcome Measures
Name Time Method Occurrence of possible side effects. Timepoint: From the time the patient arrives to the time of discharge from the hospital. Method of measurement: Investigating the presence of side effects during hospitalization.;Duration of hospital stay. Timepoint: The time of arrival to the departure of the patient from the hospital. Method of measurement: Number of days of hospitalization.;The number of Pack cell received. Timepoint: After surgery. Method of measurement: The number of cell packs.