Performance of Mid-Upper Arm Circumference for Detection of Severe Acute Malnutrition in Indonesian Under-Fives
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 421
- 试验地点
- 2
- 主要终点
- Diagnostic value of MUAC in diagnosing SAM compare to WHZ-index
研究概览
简要总结
WHO recommends 11.5 cm as a cut-off point of Mid-Upper Arm Circumference (MUAC) to detect and/or diagnose severe acute malnutrition (SAM) in under-five. MUAC is practical and useful, especially in area with limited facilities which has no standardized scale and infantometer. However, several studies showed that this cut-off need to be evaluated as it has modest detection rate for SAM. This study aims to evaluate diagnostic value of MUAC with 11.5 cm cut-off compared to WHZ as gold standard to identify SAM. The sensitivity, specificity, positive and negative predictive value of MUAC with 11.5 cm as a standard cut-off will be evaluated.
This study also aim to find new cut-off value that may offer better diagnostic performance. The main research questions were:
What is the diagnostic accuracy of Mid-Upper Arm Circumference (MUAC) compared to the Weight for Height Z Score (WHZ) in identifying SAM in children, and what is the optimal MUAC cut-off value for enhanced diagnostic performance?
研究设计
- 研究类型
- Observational
- 观察模型
- Ecologic Or Community
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 6 Months 至 59 Months（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •under-fives that 6-59 months-old
排除标准
- •hydrocephalus
- •tumor or oncologic diseases
- •organomegaly
- •uncooperative during measurement
结局指标
主要结局
Diagnostic value of MUAC in diagnosing SAM compare to WHZ-index
时间窗: 2 months
To evaluate sensitivity, specificity, positive and negative predictive value of MUAC
次要结局
- Finding new cut off value that offer better diagnostic performance using ROC(2 months)
研究者
Klara Yuliarti
Principal Investigator
Indonesia University