Effect of Grape seed oil (Grapex) on scleroderma wound healing
Phase 3
- Conditions
- scleroderma.Systemic sclerosis [scleroderma]
- Registration Number
- IRCT20201010048984N1
- Lead Sponsor
- Ahvaz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Existence of at least one active wound due to scleroderma (diffuse / limited)
Age 20 to 70 years
Patient satisfaction
Exclusion Criteria
Existence of allergy and sensitivity to grapes and their compounds,
Existence of comorbidities including diabetes, thyroid disorders, and cardiovascular disease
Addiction to alcohol, cigarettes and any drugs
Getting prostanoids (both inhaled and taken) for at least the last 3 months
Take antibiotics 2 weeks before the start of the study
Moderate to severe hepatic impairment or elevated aminotransferase levels more than 3
Existence of any kind of malignancy
Pregnancy and lactation
Reluctance to participate in the study
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Wound size. Timepoint: Every 2 weeks (end of the second week and the fourth week). Method of measurement: Wound ruler.
- Secondary Outcome Measures
Name Time Method