Effect of Acute Grape Seed Extract Supplementation on the Heart Rate Recovery in Young Individuals
- Conditions
- Healthy Young Men
- Registration Number
- NCT07137988
- Lead Sponsor
- California Baptist University
- Brief Summary
This study hypothesized that sustained sympathoexcitation via MMA slows down PHRR and that GSE supplementation is effective at improving PHRR in young individuals. 12 Participants were randomly assigned, via a double-blind, cross-over design, to either receive GSE (300mg, 2 capsules) or PL (300mg, 2 capsules), with a washout period of at least 72 hrs. between trials. A submaximal exercise test was performed using a cycle ergometer combined with isometric handgrip exercise using a handgrip dynamometer, and blood flow occlusion by placing a cuff over the brachial artery of the dominant arm. Post heart rate recovery (PHRR) was measured at 5 sec. intervals throughout the experiment. The PHRR was evaluated between GSE and PL at every min. for 300 sec.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 12
- good health, nonsmokers, those not taking medications that could affect cardiovascular function
- hypertension, muscular skeletal disorders
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method Heart rate recovery every minute and heart rate kinetics (tau) following exercise 5 min after exercise
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
California Baptist University
🇺🇸Riverside, California, United States
California Baptist University🇺🇸Riverside, California, United States