Intrapleural Fibrinolysis and DNase versus VATS for the treatment of pleural empyema: a randomized, controlled trial.

Odense Universityhospital0 个研究点目标入组 184 人开始时间: 2021年5月20日最近更新: 2024年7月8日

适应症

试验速览

暂无简介。

•> 18 years or more on the day of hospitalization
•Must be able to provide informed consent
•Acute hospitalization within the last 48 hours
•Meeting diagnostic criteria for community-induced fibropurulent stage (stage II) and the chronic organizing stage (stage III) empyema
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 164
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 20

•Breastfeeding
•Known malignant sickness and declared terminal for this
•Previous surgery (within <1 year on the same side of the thorax as where the parapneumonic effusion / pleural empyema is located
•Previously (within <1 year) hospitalized with an empyema stage II-III
•Drainage on the same side of the thorax (excluding diagnostic pleural puncture), including a pigtail
•Use of intrapleural therapy contraindicated (e.g. allergy)
•Enrollment duration at the time of diagnostic puncture > 48 hours
•Hospitalization within 7 days prior to current hospitalization

发起方

Odense Universityhospital