Prevalence of Gaucher Disease in Hematological Routine Practice – from Thrombocytopenia to Diagnosis of Gaucher Disease (PRAGMATIC-Diagnosis) - PRAGMATIC

BAG onkologische Schwerpunktpraxis0 个研究点目标入组 222 人开始时间: 2020年7月30日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•1. unexplained thrombocytopenia: Platelet count < 150x109/l at two independent measurements
•2. with unexplained thrombocytopenia (one platelet count < 150x109/l) and at least one other abnormal hematological parameter (leukocyte < 4x109/l, known serum ferritin >ULN, male patients: Hb < 8 mmol/l (13 g/dl), female patients: Hb < 7.5 mmol/l (12 g/dl)
•3. ITP and known splenomegaly (according DGHO guidelines)

•1. Patients under the age of 18
•2. Patients receiving cytopenia inducing treatment (e.g. chemotherapy)
•3. Patients unable to state informed consent for genetic testing
•4. Patients with known other causalities for thrombocytopenia e.g. viral disease (HIV, Hepatitis C), severe liver disease, autoimmune disease
•5. Patients with ITP without splenomegaly (according DGHO guidelines)
•6. Patients with comedication with a high probability to lead to thrombocytopenia

发起方

BAG onkologische Schwerpunktpraxis