Anatomical and mechanical parameters of the knee extensormuscles in patients with hemophilia and healthy participants.

Recruiting

• Conditions: Healthy control participants; D66; D67; Hereditary factor VIII deficiency; Hereditary factor IX deficiency

• Registration Number: DRKS00034095
• Lead Sponsor: Bergische Universität Wuppertal, Lehrstuhl für Sportmedizin

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-04-24
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Male
• Target Recruitment: 40

Inclusion Criteria

Adult patients with moderate and severe hemophilia A and B.
- Adult male healthy participants.

Exclusion Criteria

- Patients: acute injuries or bleeding in the lower extremities, neurological disorders, diagnosed cognitive impairments.
- Healthy participants: acute lower extremity injuries, musculoskeletal disorders, coagulation disorders, neurological disorders, diagnosed cognitive impairments.

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
- Description and correlation of anatomical and mechanical parameters of knee extensor muscles and tendons in individuals with haemophilia.

Secondary Outcome Measures

Name	Time	Method
Description and correlation of the anatomical and mechanical parameters of the knee extensor muscles and tendons in healthy subjects.<br>Differences in the anatomical and mechanical parameters of the knee extensor muscles and tendons between subjects with hemophilia and healthy subjects.<br>Correlation of the anatomical and mechanical parameters of the knee extensor muscles and tendons with the joint status in subjects with hemophilia and healthy subjects.