Preanesthetic medication in pediatric patients: A comparison of midazolam, clonidine and dexmedetomidine
Phase 1
- Conditions
- Is there a difference in anxiety- and sedation-level, and in anesthesia induction compliance between the preanesthetics included in study, in pediatric patients? Can we prevent and reduce anxiety without causing negative cardiorespiratory effects by selected preanesthetic included in study, in TIVA in pediatric patients? Does the preanesthetic used in this study prevent and/or reduce pain, vomiting, shivering, events of emergence delirium and maladaptive behaviors, without prolonging recovery?Therapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03]
- Registration Number
- EUCTR2015-003676-70-SE
- Lead Sponsor
- orrbottens läns landsting
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Authorised-recruitment may be ongoing or finished
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
Informed consent from both parents
Both genders
2-6 years of age
ASA I-II
Elective ENT-surgery
Weight: =30 kg
Language: Swedish
Are the trial subjects under 18? yes
Number of subjects for this age range: 300
F.1.2 Adults (18-64 years) no
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
ASA > II
Hypersensitive to study drug
Resent surgery
Failure of vital organs (heart, lung, liver, kidneys)
Central nervous system disorder or mental retardation
Psychotropic medical use
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method