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临床试验/NCT06180135
NCT06180135已完成不适用

The Effect Of Coffee And Tea Drink On Gis Functions Healing Quality After Surgery In Patients Surgery

Eastern Mediterranean University6 个研究点 分布在 1 个国家目标入组 108 人开始时间: 2023年8月5日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
108
试验地点
6
主要终点
Form For Evaluation Of The Patient's Gastrointestinal Functions

研究概览

简要总结

The positive effects of coffee on general health, central nervous system, cardiovascular system and bowel movements in healthy people are known. In a few studies conducted in recent years, it is stated that coffee consumption is a safe and effective method for accelerating bowel movements after surgical intervention.

It is known that many plants have been used for medicinal purposes since ancient times in the world. Among these plants is fennel (foeniculum vulgare). The fennel plant was used as a spice in Greece and Rome, as well as recognized and used for medicinal purposes. Fennel, dyspeptic ailments; it is effective in spasmodic gastrointestinal complaints, bloating, gas and upper respiratory tract disorders This research; A randomized controlled study was planned to evaluate the effects of Turkish coffee and fennel tea consumption on patients' gastrointestinal functions and healing quality after laparoscopic cholecystectomy surgery.

详细描述

Surgical interventions can be large or small, planned or urgent, but they have physiological and psychological effects on people. The most obvious physiological effects on the patient are: deterioration of organ functions and vascular system, change in body image, activation of stress-alarm reaction. Another of these physiological effects and the most common one is the changes in the gastrointestinal system. Postoperative ileus, which is defined as the temporary deterioration of gastric motility, causes pre- and postoperative diet restrictions, administration of anesthetics/narcotics, delay in gastric emptying as a result of excessive use of isotonic solutions, and slowing down in bowel movements due to excessive touching of the intestines, especially in abdominal and pelvic surgeries. It is known that current approaches and evidence-based practices regarding treatment and care in surgery can accelerate post-surgical recovery and reduce surgery-related deaths. In this direction, one of the evidence-based applications that has emerged to accelerate post-operative recovery is Enhanced Recovery After Surgery - ERAS, also known as Fast Track Surgery (FTS) protocol. With these new approaches, it has been proven that the time between the onset of bowel movements and the first gas formation is shortened, wound healing is accelerated, infection rates are reduced, and hospital stay is reduced. One of these approaches is coffee consumption in the postoperative period. Coffee is a popular beverage and its effects on general health, the central nervous system and the cardiovascular system are well known. Caffeine is a moderate central nervous system stimulant, and these effects are mediated by adenosine receptors. It acts as a potential antagonist of adenosine receptors in the nervous system. Caffeine and adenosine molecules are similar molecules. Caffeine binds to adenosine receptors, thus reducing the effectiveness of adenosine. As a result, we feel the stimulating effect of caffeine at the highest level. It has been observed that consuming more than 7 cups of coffee per day increases gastric secretion. It is also known that coffee increases bowel movements in healthy people. In a study conducted with patients who underwent laparoscopic orectal surgery, it was determined that bowel movements started 3 hours earlier than the patients in the control group and stayed one day less in the hospital. However, in the literature review, it is observed that there are very limited studies on this subject.

In the literature review, early oral feeding, mobilization and gum chewing were found to be effective in preventing paralytic ileus after abdominal and laparoscopic surgery, increasing patient comfort and shortening hospital stay. However, studies examining the effect of coffee consumption on bowel movements and hospital stay in the early postoperative period are very limited.

Based on this information, this study was planned to evaluate the effects of Turkish coffee and fennel tea drinking on GIS functions and healing quality in patients who underwent laparoscopic laparoscopic cholecystectomy surgery.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients who have undergone laparoscopic cholecystectomy under general anesthesia
  • Patients whose bowel functions do not have all chronic or metabolic features,
  • Patients without auditory, mental and past diseases
  • Patients who volunteered for the study

排除标准

  • Patients who did not receive general anesthesia and did not have laparoscopic cholecystectomy surgery
  • Those who have any chronic or metabolic disease that will affect intestinal functions,
  • Those with auditory, mental and neurological diseases,
  • Patients using drugs for psychiatric disorders,
  • who are not willing to participate in the research,
  • Patients who are intubated and sedated,
  • Those with stoma
  • Patients with previous abdominal surgery will not be included in the study.

结局指标

主要结局

Form For Evaluation Of The Patient's Gastrointestinal Functions

时间窗: one day first 6 th hour

Marking will be Yes or No. For example, is there gas output? yes/no

Quality Of Healing Scale

时间窗: one day first 6 th hour

minıimum=never maximum=always

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Gülcan Dürüst Sakallı

lecturer

Eastern Mediterranean University

研究点 (6)

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