Ability of a polyherbal formulation to treat gum inflammation and Bad breath over a period of three months
- Conditions
- gingivitis and halitosis
- Registration Number
- CTRI/2018/06/014686
- Lead Sponsor
- Dr MGR educational and Research Institute University
- Brief Summary
Commonoral health problems like gingivitis, halitosis and dentinal hypersensitivityaffect all people irrespective of age, gender and race. These conditions inparticular affect the quality of life of the individual almost on a dailybasis. In south India, studies report a prevalence of gingivitis to be 57%, and 47% from halitosis respectively. A plethoraof treatment options are available to alleviate these conditions ranging fromprofessional intervention to home care solutions, but individuals by majorityopt for home care remedies. The principal home care remedy for the treatment ofsuch common oral problems is dentifrice.
Medicateddentifrice containing chemicals such as triclosan or chlorhexidine is the goldstandard for treating gingivitis and halitosis. They have their own merits butalso causes tooth staining, taste alterations and rare instances mucosaldesquamation and microbial resistance owing to prolonged use. Further, not muchhas been explored regarding a suitable herbal alternative towards the treatmentof dentinal hypersensitivity.
Recentfocus has shifted to the anti-inflammatory and antimicrobial properties ofnatural products, because of the widespread microbial resistance as aconsequence of drug overuse. Several plants with herbal properties wereidentified through literature search and used through centuries by ourforefathers to treat several oral conditions. The principal ingredientsincluded in the phytotheraputic paste contain *Terminalia chebula, Phylathus embelica, Terminalia belerica,Glycyrrhiza glabra, Acmella oleracea, Salvadora perscia, Ficus benghalensis*among others.
Weintend to check the effectiveness of a poly herbal paste formualtion with the aforementioned components to treat conditionssuch as gingivitis and halitosis.
Aim: to evaluate the effectiveness of a polyherbal formulation to treat gingivitis and halitosis over a period of three months: A randomized controlled trial.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 30
- Patients suffering from moderate to severe gingivitis and malodor of oral origin.
- Those providing consent to participate and willing to be available for followup for 3 months.
- Systemic diseases, oral malodor from extra oral origin and those allergic to any constituents of toothpaste are excluded.
- Those not willing to provide consent and not available for followup for three months are excluded.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method reduction in gingivitis and halitosis over a period of three months 30, 60, 90 days
- Secondary Outcome Measures
Name Time Method reduction in plaque microbial load, total salivary bacterial load and total protein content 30, 60 and 90 days
Trial Locations
- Locations (1)
Thai Moogambigai Dental College and Hospital
🇮🇳Chennai, TAMIL NADU, India
Thai Moogambigai Dental College and Hospital🇮🇳Chennai, TAMIL NADU, IndiaDr Samuel Raj SrinivasanPrincipal investigator7010395428samuelrajsrinivasan@gmail.com