Serum Ferritin and Hepicidin Concentration in Chronic Periodontitis Patients With T2DM

Completed

• Conditions: Periodontitis; Type2 Diabetes

• Registration Number: NCT03964428
• Lead Sponsor: Fayoum University

Brief Summary

serum level of ferritin and hepicidin were evaluated in periodontitis patient with and without type 2 diabetes before and after non surgical periodontal treatment to clarify their in periodontal disease

Detailed Description

Not available

Study Timeline

• Study Start: 2018-09-01
• Primary Completion: 2019-01-30
• Study Completion: 2019-01-30
• Study First Submitted: 2019-05-23
• Study First Submitted QC: 2019-05-24
• Study First Posted: 2019-05-28
• Status Verified: 2019-06
• Last Update Submitted: 2019-06-08
• Last Update Posted: 2019-06-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• patients with more than 30% of the sites had clinical attachment level (CAL) 3-4mm with T2DM
• systemically healthy patients with more than 30% of the sites had clinical attachment level (CAL) 3-4mm
• healthy subjects had clinically healthy gingiva with ≤ 3mm pocket probing depth (PPD), nearly zero plaque index (PI), gingival index (GI), zero CAL.

Exclusion Criteria

• (I) Pregnancy or lactation, (II) History of receiving professional periodontal treatment during the past 6 months; (III) Treatment with any type of medications and/ or antibiotics during the past 3 months and (IV) Current or former smokers.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ferritin concentration	0-3 months	ng/ml
hepicidin concentration	0-3 months	ng/ml

Trial Locations

Locations (1)

Nayroz Abelfattah Tarrad; 🇪🇬 Cairo, Egypt