Combined high-resolution manometry and impedance measurement as diagnostic tools in the rumination syndrome
- Conditions
- vomiting10017977
- Registration Number
- NL-OMON34476
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 22
Inclusion Criteria
11 patients with rumination syndrome
11 patients with initial complaints of regurgitation or vomiting but without clinical diagnosis of rumination syndrome
Exclusion Criteria
Surgery of the GI tract other than appendectomy or cholecystectomy
Inability to stop the use of medication influencing GI motility for one week
Inability to stop the use of proton pump inhibitors for one week
Abnormal endoscopic gastroesophageal findings other than esophagitis or hiatal hernia
Abdominal ultrasound and/or abdominal x-ray suspective of intestinal obstruction
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The occurrence of a specific gastroesophageal pressure-flow pattern immediately<br /><br>before or simultaneously with the regurgitation event</p><br>
- Secondary Outcome Measures
Name Time Method <p>Other esophageal and intragastric pressure tracings<br /><br>Esophageal pH-metry tracings<br /><br>Esophageal impedance tracings</p><br>