Can blood flow variations in the brain be used to assess confusional state in heart failure patients admitted to Cardiac Intensive care unit.

Not Applicable

• Conditions: Health Condition 1: I509- Heart failure, unspecified

• Registration Number: CTRI/2024/03/063517
• Lead Sponsor: Dr Vimal Bhardwaj

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 1 April 2024

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

All ICU patients aged more than 18 years admitted with decompensated heart failure with the any one of the following:

1.Not requiring invasive mechanical ventilation

2.Intubated patients with RASS score of more than -3

3.Patients in shock with Vasoactive inotropic score less than 5

Exclusion Criteria

1. Patient or the primary caregiver not giving consent.

2. Patients with poor transcranial window

3. Patients with abnormal findings on brain imaging, if available

4. Patients with PaO2 less than 60mm hg on the day of TCD screening.

5. PaCO2 less than 32mm hg or more than 45mm hg on the day of TCD screening.

6. Past history of cognitive disorders

7. Previous or current Stroke/intracranial bleeding

8. Hypothermia with core body temperature less than 34 degree celsius on the day of TCD screening.

9. Hypertension with blood pressure more than 180/110 mm hg during TCD screening.

10. Hypotension with mean arterial pressure less than 60 mm hg during TCD screening.

11. RAAS Score of more than +2 during TCD screening.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To explore if serial transcranial blood flow velocity measurement by a bedside ultrasound Doppler <br/ ><br>can be used as a screening tool to predict delirium in decompensated heart failure patients admitted to cardiac ICU.Timepoint: Until in IC

Secondary Outcome Measures

Name	Time	Method
To determine if abnormal VExUS scores are associated with a higher risk of delirium.Timepoint: Until in ICU;To determine the relationship between VExUS scoring and TCD measurements.Timepoint: Until in IC