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Clinical Trials/NCT03010813
NCT03010813
Completed
Not Applicable

A Novel Robotic System for Single Port and Natural Orifice Transluminal Endoscopic Surgery: A Prospective, Single Center, Multispecialty Study

Chinese University of Hong Kong1 site in 1 country63 target enrollmentDecember 2016

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Colorectal Neoplasms
Sponsor
Chinese University of Hong Kong
Enrollment
63
Locations
1
Primary Endpoint
Conversion rate
Status
Completed
Last Updated
8 years ago

Overview

Brief Summary

This is a prospective, single center, multispecialty study that aimed to evaluate the clinical feasibility and safety of single port surgery and NOTES (mainly transanal and transoral surgery) using a novel single port robotic system.

Detailed Description

Background: Single port surgery and natural orifice transluminal endoscopic surgery (NOTES) are emerging minimally invasive surgery techniques which can further reduce patient trauma and enhance recovery. However, the wider adoption of these techniques is hampered by the limitation of instrumentation and technical difficulties. Robotic assistance may improve surgical capabilities during single port surgery and NOTES by providing augmented motion precision and manipulation dexterity. Objectives: To evaluate the clinical feasibility and safety of single port surgery and NOTES (mainly transanal and transoral surgery) using a novel single port robotic system. Design: Prospective, single center, multispecialty study consistent with a stage 1 (Innovation) study described in the Innovation, Development, Exploration, Assessment, Long-term Study (IDEAL) framework. Subjects: Sixty consecutive patients with various benign/malignant pathologies indicated for single port colorectal/urologic surgery or transanal/transoral surgery who fulfilled all the inclusion and exclusion criteria will be recruited. Intervention: Single port surgery and transanal/transoral surgery will be performed using the novel single port robotic system. Study Endpoints: Primary: conversion rate and perioperative complications. Secondary: operative time, blood loss, pain scores, analgesic requirement, and length of stay. Hypothesis: The prospective study will provide important information on the feasibility, safety, and effectiveness of the novel single port robotic system in performing single port surgery and NOTES in various surgical specialties. A positive study will provide supporting evidence for continuing development of this new technology.

Registry
clinicaltrials.gov
Start Date
December 2016
End Date
October 2017
Last Updated
8 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Simon S. M. Ng

Professor of Surgery

Chinese University of Hong Kong

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Conversion rate

Time Frame: Up to 1 month

An emergent change in the treatment plan to conventional minimally invasive (laparoscopic/endoscopic) surgery (i.e. the use of more than one additional port), multiport robotic surgery, or to open surgery

Perioperative complications

Time Frame: Up to 1 month

Complications including intraoperative complications and all complications occurring during the hospital stay or within 30 days after discharge will be graded according to the Clavien-Dindo classification

Secondary Outcomes

  • Operative time(Intraoperative)
  • Estimated blood loss(Up to 1 month)
  • Pain scores on a visual analog scale(Up to 1 month)
  • Analgesic requirement(Up to 1 month)
  • Length of hospital stay(Up to 1 month)
  • Completeness of resection(Up to 1 month)
  • Resection margins(Up to 1 month)
  • Number of lymph nodes harvested(Up to 1 month)
  • Anal continence after transanal surgery(Up to 1 year)
  • Fecal incontinence quality of life after transanal surgery(Up to 1 year)
  • Urinary continence after radical prostatectomy(Up to 1 year)
  • Male sexual function after radical prostatectomy(Up to 1 year)
  • Renal function after nephrectomy(Up to 1 year)
  • Swallowing function after transoral robotic surgery (TORS)(Up to 1 year)
  • Voice function after TORS(Up to 1 year)

Study Sites (1)

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