CBT for Obsessive compulsive disorder
- Conditions
- Health Condition 1: F422- Mixed obsessional thoughts and actsHealth Condition 2: null- Obsessive Compulsive Disorder
- Registration Number
- CTRI/2016/01/006479
- Lead Sponsor
- Indian Council for Medical Research ICMR New Delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 43
1. Patients fulfilling the criteria for primary diagnosis of Obsessive Compulsive Disorder according to DSM-IV. (300.3).
2. Age-18 â??50 years.
3.Patient with both obsessions and compulsions (Mixed subtype of OCD).
Partial treatment response to adequate trial with at least one of the SRIs.
Y â?? BOCS Symptom severity score of 16 and above.
4. Symptom duration of at least 1 year.
5. Stabilized on medications for at least 4 weeks prior to recruitment.
1.A primary diagnosis of schizophrenia, bipolar affective disorder, severe depression, mental retardation, epilepsy, head injury or other neurological disorders.
2.Substance use, dependence, excepting Nicotine dependence in the past 6 months prior to recruitment.
3.Previous exposure to structured cognitive behaviour therapy for obsessive-compulsive disorder (15 sessions or more of CBT comprising of exposure and response prevention) in the last 6 months.
4.Symptom duration greater than 15 years.
5.Pregnancy, nursing or any other unstable medical condition
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Symptom severity on Yale Brown obsessive compulsive scale YBOCS- at baseline mid and post therapy <br/ ><br>CGI-Scale (improvement) at post therapy <br/ ><br>at post therapyTimepoint: Yale Brown obsessive compulsive scale YBOCS- at baseline- mid therapy <br/ ><br>CGI-Scale (improvement) <br/ ><br>at mid and post therapy
- Secondary Outcome Measures
Name Time Method HAMD (depression)HARS, (anxiety), functioning, Quality of lifeTimepoint: Baseline, post and follow-up