Role of tonsilar epithelium in oral tolerance
- Conditions
- AllergienT78.4Allergy, unspecified
- Registration Number
- DRKS00005424
- Lead Sponsor
- Zentrum für Kinder- und Jugendmedizin der Universitätsklinik Freiburg, Arbeitsgruppe Allergologie, Pulmologie und Cystische Fibrose
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Enclosed will be children, aged 1 to 17 years, both sexes, which have to undergo tonsillectomy or adenotomy of medical reasons.
Exclusion Criteria
Disclosed will be children whose tonsils or adenoids are inflammed or show cysts or malignancies.
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Frequency and composition of Treg, structure and amount of tonsilar E-Cadherin in tonsilar epithelial cells by FACS and by immunofluorescence
- Secondary Outcome Measures
Name Time Method proliferation of T-cells with and without regulatory T cells