Comparison of the analgesic efficacy of combined peri-articular hypertonic dextrose prolotherapy, intra-articular Magnesium and Ozone (Dextrose Magnesium Ozone Therapy) with Intra articular Corticosteroid in the management of moderate-severe Osteoarthritis of the Knee: Randomized Double-Blind, Placebo-controlled Trial - NI

Sri Madhusudan Sai Institute of Medical Sciences and Research,0 个研究点目标入组 0 人开始时间: 待定最近更新: 2023年12月19日

试验速览

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•Adult patients aged 40 years and above, who meet the American College of Rheumatology criteria for osteoarthritis (knee pain for most of the days of the previous month and osteophyte (s) at the joint line visible on X ray) 29, are willing to consent and have moderate-severe OAK.
•Clinical Severity: Patients should have a mean score of 1.5 - 3.5 on WOMAC A sub score30, 31.
•Radiological Severity of Osteoarthritis of the knee is based on the criteria defined by Kellgren and Lawrence, which grades OAK into 0-4 grades32. This study will be including Grade 3 and Grade 4 Osteoarthritis of the knee

•Participants unwilling to provide consent
•Patients with mild OAK
•Participants with known history of drug allergy to bupivacaine, corticosteroid or lidocaine
•Patients on anticoagulant or antiplatelet medication
•Patients who have had a myocardial infraction in the last 6 months
•Patients with secondary OAK (gout, RA, Psoriasis) or generalized osteoarthritis
•Patients who have received intra articular steroids into any joint within 3 months

发起方

Sri Madhusudan Sai Institute of Medical Sciences and Research,