ISRCTN81979106
Completed
Not Applicable
An eight week pilot study to investigate the effect of High-Frequency Airway Oscillation on breathlessness in patients with Chronic Obstructive Pulmonary Disease: a single arm interventional trial
niversity Hospitals of Leicester0 sites24 target enrollmentMay 24, 2016
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Chronic obstructive pulmonary disease (COPD)
- Sponsor
- niversity Hospitals of Leicester
- Enrollment
- 24
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
- 2018 results in https://www.ncbi.nlm.nih.gov/pubmed/29535259 (added 24/01/2019)
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Participant is willing and able to give informed consent for participation in the study
- •2\. Male or Female, aged 40 years or above
- •3\. Confirmed diagnosed of COPD
- •4\. MRC Score of 3 or more. (walk slower than people of the same age on the level or stops for breath when walking at own pace on the level)
- •5\. Able to read and write in English
Exclusion Criteria
- •1\. Significant disease (other than COPD) that could cause dyspnoea or exercise limitation
- •2\. Contraindications for exercise (unstable cardiovascular disease; hypertension etc, a full list is described by the American College of Sports Medicine and is routine deployed)
- •3\. Inability/unwillingness to use the device
- •4\. Contraindications to using HFAO device (including severe right heart failure with hypotension), current severe haemoptysis, ineffective cough, rib fractures, pregnancy, current or recent pneumothorax, epilepsy, current pulmonary embolism, oesophageal varices, recent thoracic, upper gastro\-intestinal tract or facial surgery)
- •5\. Previously engaged in exercised based research or pulmonary rehab in the last 6 months.
- •6\. Inability to secure informed consent
- •7\. Those unable to communicate in full English will be excluded as the user manual is only available in English
Outcomes
Primary Outcomes
Not specified
Similar Trials
Completed
Not Applicable
A trial of antipsychotic medication in comparison to cognitive behaviour therapy or a combination of both in adults with psychosisTopic: Mental Health Research NetworkSubtopic: Schizophrenia, PsychosisDisease: Schizophrenia, PsychosisMental and Behavioural DisordersSchizophreniaISRCTN06022197Greater Manchester West Mental Health NHS Foundation Trust (UK)75
Completed
Not Applicable
Reducing implant infection in orthopaedics (RIIiO) pilot studySpecialty: Infectious diseases and microbiology, Primary sub-specialty: Infection preventionUKCRC code/ Disease: Infection/ Bacterial, viral and other infectious agents, Injuries and Accidents/ Injuries to the hip and thighInfections and InfestationsInfection following hip fractureISRCTN74612906Brighton and Sussex University Hospitals NHS Trust515
Completed
Not Applicable
Efficacy of patient-controlled paravertebral block for single intercostal video assisted thoracic surgeryPain in the postoperative periodSigns and SymptomsISRCTN24097424Second Affiliated Hospital of Zhejiang University260
Completed
Not Applicable
The treatment of severe atopic eczema trial (TREAT)Topic: Children, DermatologySubtopic: Children (all Diagnoses), Dermatology (Skin)Disease: All Diseases, DermatologySkin and Connective Tissue DiseasesSevere atopic eczemaISRCTN15837754King's College London (UK)103
Completed
Phase 1
Efficacy and safety of olaparib in relapsed and refractory chronic lymphocytic leukaemia patients with an 11q deletion or ATM mutation and relapsed/refractory patients with T-prolymphocytic leukaemia and mantle cell lymphomaChronic lymphocytic leukaemiaCancerLymphoid leukaemiaISRCTN34386131niversity of Birmingham (UK)15