Contracture management in Duchenne muscular dystrophy

Not Applicable

Completed

• Conditions: Duchenne muscular dystrophy; Musculoskeletal Diseases

• Registration Number: ISRCTN18436655
• Lead Sponsor: ewcastle upon Tyne Hospitals NHS Foundation Trust

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2022-12-02
• Study Start: 2024-02-09
• Last Update Posted: 19 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Male
• Target Recruitment: 5

Inclusion Criteria

primary submission:
1. Genetic diagnosis of DMD
2. Ankle ROM of between +10 degrees of dorsiflexion and -10 degrees of dorsiflexion.
3. On assessment ROM has either deteriorated or remained the same since prior appointment despite good adherence to current stretching regime
4. Aged between 4 and 10 years of age
5. Orthotic naïve

AMENDMENT to inclusion criteria: Re-submission:
1. Ankle orthotic naïve or supplied with an AFO in the last 18 months that currently fits well
2. From JWMDRC clinics or referred to us by a centre which borders us
3. Email or written evidence that the local specialist team are amenable to our oversight of orthotics for the duration of the study

Exclusion Criteria

1. Significant behavioural issues that would make adherence problematic
2. Previous or current lower limb fracture within the last year
3. Previous tenotomy or other interventions for contracture management
4. Non-English speaking

Study & Design

• Study Type: Interventional
• Study Design: Not specified