Quantitative MR imaging in locally advanced cervical cancer
Recruiting
- Conditions
- Cervical cancer1002765610013364
- Registration Number
- NL-OMON55543
- Lead Sponsor
- eids Universitair Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 160
Inclusion Criteria
* Patients included in the EMBRACE II study (see inclusion criteria in the
EMBRACE II protocol)
* Patients without previous record of allergic reaction to infusion of protocol
related contrast media (Gadolinium-based)
* Patients with sufficient kidney function according to local regulations
Exclusion Criteria
* According to EMBRACE II protocol
* Patients with active infection or severe medical condition
* GFR < 30 ml/min/1,73 m²
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Kinetic modelling will be applied in DCE-MRI images to assess quantitative<br /><br>kinetic parameters in the gross tumour volume related to blood volume,<br /><br>interstitial volume, flow and permeability. It will be tested whether different<br /><br>thresholds of haemodynamic parameters can predict disease free survival.</p><br>
- Secondary Outcome Measures
Name Time Method