A Randomized, Controlled Trial Reviewing the Effectiveness of a Preventative Delirium Protocol in Elderly Patients While Analyzing Its Consequential Effects on Awareness, PONV, and/or Pain Control
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Delirium
- Sponsor
- Rush University Medical Center
- Enrollment
- 263
- Locations
- 1
- Primary Endpoint
- Presence or absence of Delirium (CAM_ICU)
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
The current study aims to elucidate the effectiveness of a preventative delirium protocol in patients older than 65 years of age undergoing elective surgery.
Detailed Description
A comprehensive analysis of patient specific risk factors and predisposing perioperative risk factors will be completed. The objective is to see if delirium incidences are significantly lower in the group that receives a preventative delirium protocol compared to a control group, while not increasing other adverse undesirable side effects. We hypothesize that a preventative delirium protocol will reduce the incidence of delirium compared to the control group (primary outcome), but this protocol may lead to increased side effects such as PONV, poor pain control, and increased awareness (secondary outcomes).
Investigators
Asokumar Buvanendran
Professor of Anesthesiology
Rush University Medical Center
Eligibility Criteria
Inclusion Criteria
- •Age \> 65 years
- •Scheduled for Elective Surgery (outpatient/same-day admit)
Exclusion Criteria
- •Need emergency surgery
- •Need intracranial surgery
- •Dependent on opiate narcotics
- •Surgeon-specified perioperative procedures that precludes the current study's protocol
Outcomes
Primary Outcomes
Presence or absence of Delirium (CAM_ICU)
Time Frame: Within one post-operative day
Delirium defined by Post-operative CAM, using the validated CAM-ICU measure
Secondary Outcomes
- NRS Pain(Within one post-operative day)
- PONV(Within one post-operative day)