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Clinical Trials/NCT05498532
NCT05498532
Unknown
Not Applicable

Functional MRI Usage for Pyelo-ureteral Junction Syndrome : Results of Nancy Children Hospital Cohort

Central Hospital, Nancy, France1 site in 1 country270 target enrollmentSeptember 1, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Stricture of Pelviureteric Juncture
Sponsor
Central Hospital, Nancy, France
Enrollment
270
Locations
1
Primary Endpoint
MRI and scintigraphy differential renal function correlation
Last Updated
3 years ago

Overview

Brief Summary

Pyelo-ureteral junction syndrome is the most common urological abnormality in children.

Functional MRI has been evaluated several times, and had shown good correlation with scintigraphy, but tends to over estimate results. Moreover, those studies included a small number of cases. Its sensitivity to detect crossing polar vessel is limited.

We aimed to evaluate, in patients between 0 and 1 year old, the correlation between MRI and scintigraphy differential renal function.

Our secondary objectives are : evaluation of MRI performances to detect polar vessel ; comparison of surgery times depending of MRI only realisation or MRI and scintigraphy realisation.

Registry
clinicaltrials.gov
Start Date
September 1, 2022
End Date
December 30, 2022
Last Updated
3 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Central Hospital, Nancy, France
Responsible Party
Principal Investigator
Principal Investigator

Charles Mazeaud

Praticien hospitalier universitaire

Central Hospital, Nancy, France

Eligibility Criteria

Inclusion Criteria

  • children between 0 and 17 years old
  • followed for pyelo-ureteral junction syndrome

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

MRI and scintigraphy differential renal function correlation

Time Frame: from january 2007 to december 2021

Evaluation of differential renal function between MRI and scintigraphy in children between 0 and 1 year old ; Pearson correlation coefficient

Secondary Outcomes

  • performance of MRI in detecting polar vessel(from january 2007 to december 2021)
  • MRI and scintigraphy differential renal function correlation in operated patient(from january 2007 to december 2021)
  • Time difference in patient operated for PUJS depending on MRI realisation ou MRI and scintigraphy realisation(from january 2007 to december 2021)

Study Sites (1)

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