The Glycaemic Response of Local Foods Using the Continuous Glucose Monitoring System
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 15
- 试验地点
- 2
- 主要终点
- Daily blood glucose profile
研究概览
简要总结
This study is carried out to determine the effect of high and low GI of local foods using Continuous Glucose Monitoring System (CGMS™) on 24 hour blood glucose profiles.
详细描述
Glycemic Index (GI) is a method of classifying foods based on the food's ability to raise the blood glucose level. Low GI foods are recommended as Participants will have a lower impact on blood glucose concentrations. The research sets out to determine the effect of GI on 24 hour blood glucose profiles in healthy Chinese male participants. There will be two test sessions where participants will consume either a high or low GI breakfast, lunch, snack and dinner. Participants will take part in two test sessions (each spanning over 3 days and to monitor the participants' glycemic response using a Continuous Glucose Monitoring System (CGMS) throughout the period.This study specifically attempts to see how having high and low GI locally consumed meals impact on blood glucose.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 21 Years 至 50 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Chinese, male
- •Age between 21-50 years
- •Body mass index between 18 to 25 kg/m2
- •Normal blood pressure (<140/90 Hgmm)
- •Fasting blood glucose < 6 mmol/L
排除标准
- •Current Smoker
- •Have any metabolic diseases (such as diabetes, hypertension etc)
- •Have known glucose-6-phosphate dehydrogenase deficiency (G6PD deficiency)
- •have medical conditions and/or taking medications known to affect glycaemia (glucocorticoids, thyroid hormones, thiazide diuretics)
- •Have an ongoing infection or currently undergoing treatment at the time of screening
- •Known Chronic infection or known to suffer from or have previously suffered from or is a carrier of Hepatitis B Virus (HBV), Hepatitis C Virus (HCV), Human Immunodeficiency Virus (HIV)• Have active Tuberculosis (TB) or currently receiving treatment for TB
- •Have intolerances or allergies to any foods
- •Partake in sports at the competitive and/or endurance levels
结局指标
主要结局
Daily blood glucose profile
时间窗: 24 hours
The daily total blood glucose response is measured for each low and high GI treatment as the area under the curve over 24 hours using CGMS for breakfast, lunch, snack and dinner.
次要结局
未报告次要终点
研究者
JeyaKumar Henry
Principal Investigator
Clinical Nutrition Research Centre, Singapore