The effect of misoprostol on the therapeutic abortio
Phase 2
- Conditions
- medical management of second trimester induced abortion.Medical abortion
- Registration Number
- IRCT2013120315634N1
- Lead Sponsor
- Vice-Chancellor for Research, Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 91
Inclusion Criteria
healthy pregnant women in their second trimester of pregnancy (14-20 weeks) with closed cervix who are candidate for therapeutic abortion and agree to participate in this clinical trial.
Exclusion criteria: history of more than 2 cesarean section; history of cesarean section with uterine classic or T-shape incision; previous myomectomy; allergy to prostaglandins; severe vaginal bleeding before treatment; anemia Hb less than 7 g/dl ); coagulopathy; significant medical disorder(example, active liver disease, cardiovascular disease, renal failure, chronic adrenal failure, disorders requiring corticosteroid therapy); rupture of membrane and vaginitis.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Complete abortion rate at 24 and 48 hours. Timepoint: every 6 hours. Method of measurement: Questioneaire.
- Secondary Outcome Measures
Name Time Method Failure rate. Timepoint: No abortions occurred in 48 hours. Method of measurement: sonography.;Side effects of drug. Timepoint: Every 6 hours. Method of measurement: Questionnaire.;Induction abortion interval from insertion of first dose of misoprostol. Timepoint: Every 6 hours. Method of measurement: hour.