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Clinical Trials/NCT05014763
NCT05014763
Unknown
Not Applicable

Comparison of Peri-implant Tissue Stability Following Soft Tissue Augmentation Harvested From the Deep Palate or the Tuberosity Area: A Randomized Controlled Clinical Trial

Tehran University of Medical Sciences1 site in 1 country34 target enrollmentSeptember 20, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Alveolar Ridge Augmentation
Sponsor
Tehran University of Medical Sciences
Enrollment
34
Locations
1
Primary Endpoint
soft tissue volume change 0-3
Last Updated
4 years ago

Overview

Brief Summary

This study will compare peri implant tissue stability following connective tissue graft harvested fromLateral Palate or the Tuberosity Area. As far as we know, it remains controversial whether peri-implant soft tissue stability could be achieved after soft tissue augmentation with the connective tissue graft from the tuberosity or the lateral palate. Soft tissue stability evaluated by intra oral scanner will be described as primary outcome.

Detailed Description

Ridge resorption is a common finding after tooth extraction. Recently, there is an increasing concern about this issue during implant-supported reconstruction in the esthetic zone. Although the previous studies supports the guided bone regeneration procedures for reconstruction of contour deficiencies, the replacement of the mineralized materials with the bone has been questioned. Therefore, recently, using connective tissue grafts instead of allogenic or xenogenic materials has been addressed. The palate is routinely used as the donor site for harvesting the connective tissue graft. The graft can be harvested by de-epithelialized method or it can be harvested conventionally from deep palate during flap elevation. Another choice for harvesting the connective tissue graft is the tuberosity area, which can be used when you need small to moderate amount of soft tissue (around 1-2 implants). The connective tissues harvested from these sites have quite different characteristics, which might influence on the fate of the treatment in terms of the stability. therefore, we decided to compare the stability of the grafts harvested from the deep palate or tuberosity.

Registry
clinicaltrials.gov
Start Date
September 20, 2021
End Date
December 20, 2022
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • more than 18 years old.
  • systemically and periodontally healthy patients.
  • need of single implant placement between two maxillary teeth.
  • need of tissue augmentation due to concavity or soft tissue thickness less than 2 millimetres .
  • more than 3 month after extraction.
  • full mouth plaque index lesser than 20%.
  • sufficient mesiodistal and buccolingual space.
  • At least 10 millimetres mesiodistal dimension in tuberosity.
  • sufficient implant primary stability.
  • at least 6 mm crestal ridge width.

Exclusion Criteria

  • History of periodontitis and radiotherapy.
  • Need of horizontal ridge augmentation.
  • Previous soft tissue augmentation.
  • Heavy smoker( more than 10 cigarette per day)
  • Local or systemic conditions that would interfere with routine periodontal therapy.

Outcomes

Primary Outcomes

soft tissue volume change 0-3

Time Frame: from baseline (immediately before surgery) to 3 months

changes of soft tissue volume from baseline (immediately before surgery) to 3 months by intra oral scanner

soft tissue volume change 0-6

Time Frame: from baseline (immediately before surgery) to 6 months

changes of soft tissue volume from baseline (immediately before surgery) to 6 months by intra oral scanner

soft tissue volume change 3-6

Time Frame: from 3 months to 6 months

changes of soft tissue volume from 3 months to 6 months by intra oral scanner

Secondary Outcomes

  • The level of the pain by questionnaire through visual analogue scale(day 7)
  • Palliative 0-7(immediately after surgery to 7 days later)
  • Pink aesthetic score(6 months after surgery)

Study Sites (1)

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