ong-term follow-up after live kidney donation; A matched, controlled study on renal function and quality of life.
Completed
- Conditions
- Kidney function100028611003843010057166
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 1080
Inclusion Criteria
All donors that underwent a live donor nephrectomy between 1981 en 2010 are eligible for inclusion. Donors that have deceased will not be approached.
Exclusion Criteria
Donors must be capable of filling out the questionnaires in Dutch.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Kidney function, measured by serum creatinin and estimated GFR (calculated by<br /><br>the MDRD and CKD-EPI-formula).</p><br>
- Secondary Outcome Measures
Name Time Method <p>o Donor survival<br /><br>o Incidence of hypertension<br /><br>o Incidence of diabetes mellitus<br /><br>o Systolic and diastolic bloodpressure<br /><br>o Size of the contralateral kidney on ultrasonography<br /><br>o Quality of life, measured by the SF-12 and EuroQoL questionnaires<br /><br>o Incidence of fatal and non-fatal cardiovasculair events<br /><br>o Protein/creatinine ratio and microalbuminuria<br /><br>o Creatinine in urine<br /><br>o Glucose in blood and urine<br /><br>o Mental state: depression, anxiety, happiness, sexuality, sleep disorders<br /><br></p><br>