ong term follow-up of perichondrial transplants for the repair of cartilage defects in the human knee by 7 tesla MRI

Completed

• Conditions: cartilage defect; osteochondral defect; 10043237

• Registration Number: NL-OMON45034
• Lead Sponsor: Maastricht Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 14

Inclusion Criteria

Age > 18 years old
Underwent perichondrial tranplantation in MUMC or autologous chondrocyte transplantation in Sweden between 1986 and 1996.

Exclusion Criteria

- Knee arthroplasty in area of transplant (i.e. total-, hemi- knee arthroplasty)
- Major surgery of transplant in the knee (e.g. patellectomy, microfracture)
- Osteoartritis (grade 4 kellgren and Lawrence scale)
- Systemic diseases (e.g. DM II, Rheumatoid arthritis)
- Not able to undergo MRI scanning (metal objects in body, tattoo, etc.)

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameter is the difference of cartilage quality between the PT<br /><br>and ACT group assessed by 7T MRI.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>1. Quality of cartilage transplant compared to radiographic Kellgren-Lawrence<br /><br>OA grade.<br /><br>2. Quality of cartilage transplant compared to functionality of the treated<br /><br>knee; KOOS, ICRS-score<br /><br>3. Quality of cartilage transplant compared to level of pain in the treated<br /><br>knee; VAS-score</p><br>