跳至主要内容
临床试验/NCT02817308
NCT02817308Unknown不适用

Correlation of Serum CA19-9 Levels With Levels in Saliva and Urine of Patients With Ductal Adenocarcinoma of the Pancreas

Rambam Health Care Campus1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2016年7月最近更新:
适应症
干预措施

试验速览

阶段
不适用
入组人数
100
试验地点
1
主要终点
correlation of CA19-9 levels in urine and saliva with those in the serum

研究概览

简要总结

Ductal adenocarcinoma of the pancreas is the fifth leading cause of cancer related deaths in the European Union. Tumor markers CA19-9 and carcinoembryonic antigen are important components in decision making and follow-up of patients diagnosed with this disease.

These tumor markers were found to be elevated not only in the serum but also in other body fluids in patients with malignant lesions of the parotid gland and the urinary tract. The authors have described in a previews small preliminary study a positive and a strong linear correlation between the levels of CA19-9 in urine and saliva with those presented in the serum of patients with ductal adenocarcinoma of the pancreas. The current study seeks to enlarge the study population to confirm the previous results and standardize the measured levels of CA19-9 in these body fluids.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Parallel
主要目的
Diagnostic
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Proven diagnosis of ductal adenocarcinoma of the pancreas
  • elevated levels of CA19-9
  • possible elevated levels of CEA

排除标准

  • Previous diagnosis of malignancy

研究组 & 干预措施

Patients

Experimental

Patients with a proven diagnosis of ductal adenocarcinoma of the pancreas with elevated levels of CA19-9 and possibly elevated CEA levels.

intervention: samples of blood, saliva and urine

干预措施: samples of blood, saliva and urine (Other)

Control

Other

Patients or healthy volunteers with out a known evidence of malignancy with presumably normal levels of CA19-9 and CEA.

intervention: samples of blood, saliva and urine

干预措施: samples of blood, saliva and urine (Other)

结局指标

主要结局

correlation of CA19-9 levels in urine and saliva with those in the serum

时间窗: 1 year

次要结局

  • Number of participants needed to standardize the measurements in urine and saliva according to those measured in the serum.(1 year)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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