The Effect of Creatine Supplementation on Cognitive and Physical Tests
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 14
- 试验地点
- 1
- 主要终点
- Cognitive performance - change in accuracy (%) during a 90-min cognitive task (i.e. Stroop task)
研究概览
简要总结
To assess whether brain creatine availability has an effect on cognition. To do so we will seek to increase brain creatine concentration via a creatine supplementation protocol.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy (No neurological illness including cardiovascular, renal, and endocrine disorder)
- •Male/female
- •No medication / supplements
- •Non-smoker
- •Low to moderately active
- •Between 18 and 35 years old
排除标准
- •Use of medication
- •Use of creatine in the last 3 months
- •History of head trauma or seizure
- •Vegetarian diet [24]
- •Not being able to follow up the restrictions and prohibitions for the subjects (see Restrictions and prohibitions for the subjects)
研究组 & 干预措施
Placebo supplementation
7-day calcium lactate supplementation
干预措施: Calcium lactate (Dietary Supplement)
Creatine supplementation
7-day creatine supplementation
干预措施: Creatine (Dietary Supplement)
结局指标
主要结局
Cognitive performance - change in accuracy (%) during a 90-min cognitive task (i.e. Stroop task)
时间窗: During both lab visits (i.e. after both 7-day supplementation protocols); Accuracy (%) will be assessed during both lab visits with a 90-min cognitive task; Accuracy during the 90-min task will be reported as mean accuracy during 8 blocks of 11min15sec
Accuracy (in %) will be assessed during a cognitive task, this cognitive task will be completed after both 7-day supplementation protocols (i.e. placebo and creatine)
Cognitive performance - change in reaction time (milliseconds) during a 90-min cognitive task (i.e. Stroop task)
时间窗: During both lab visits (i.e. after both 7-day supplementation protocols); Reaction time (RT) will be assessed during both lab visits with a 90-min cognitive task; RT during the 90-min task will be reported as mean RT during 8 blocks of 11min15sec
Reaction time (in milliseconds) will be assessed during a cognitive task, this cognitive task will be completed after both 7-day supplementation protocols (i.e. placebo and creatine)
次要结局
- Physical performance - reaction time (milliseconds) during a 7-min visuomotor reaction time task(During both lab visits (i.e. after both 7-day supplementation protocols); visuomotor reaction time will be assessed during both lab visits with a 7-min visuomotor reaction time task.)
研究者
Romain Meeusen
Principal Investigator
Vrije Universiteit Brussel