Central and Peripheral Arterial Pressure Decoupling In Cardio-Pulmonary Bypass

Not Applicable

Completed

• Conditions: Cardiac Surgery; Extracorporeal Circulation; Cardiopulmonary Bypass
• Interventions: Procedure: Non-invasive blood pressure oscillometer (NIBP) implementation

• Registration Number: NCT02652858
• Lead Sponsor: Hospices Civils de Lyon

Brief Summary

Central and peripheral arterial pressure decoupling occurs in some clinical conditions like sepsis or cardiopulmonary bypass. This decoupling may leed to unsuitable decisions such as the use of catecholamines.

The aim of this study is to evaluate the pulse wave's speed as a marker of central and peripheral arterial pressure decoupling in a scheduled condition which is the cardiopulmonary bypass during cardiac surgery.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2016-01
• Study First Submitted: 2016-01-06
• Study First Submitted QC: 2016-01-08
• Study First Posted: 2016-01-12
• Primary Completion: 2016-09
• Study Completion: 2016-09
• Status Verified: 2016-10
• Last Update Submitted: 2016-10-07
• Last Update Posted: 2016-10-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Scheduled patient for coronary or valvular surgery with cardiopulmonary bypass
• Cardiopulmonary bypass is at least 90 minutes
• Written consent is needed

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Exclusion Criteria

• Patient with heart rate disorder
• Patient with aortic dissection
• Dobutamine/milrinone/levosimendan treatment before surgery
• Patient with heart rate due to a pacemaker

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Pulse wave's speed observational arm	Non-invasive blood pressure oscillometer (NIBP) implementation	Whole patients for who the pulse wave's speed are measured during a cardiopulmonary bypass during cardiac surgery

Primary Outcome Measures

Name	Time	Method
Measurement of femoral, radial and humeral pulses during a cardiopulmonary by-pass (CPBP).	Day one (6 times)	Pulse wave's speed is calculated using 1) time between ECG R-wave and local detection of the pulse wave (femoral, humeral and radial) 2) a length from heart to these sites.; Wave detection at femoral and humeral sites will use oscillometry and wave detection at radial site will use an invasive catheter which is always set for this surgery.

Trial Locations

Locations (1)

Hospices Civils de Lyon; 🇫🇷 Bron, France