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Clinical Trials/NCT02652858
NCT02652858
Completed
Not Applicable

Central and Peripheral Arterial Pressure Decoupling In Cardio-Pulmonary Bypass

Hospices Civils de Lyon1 site in 1 country40 target enrollmentJanuary 1, 2016

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cardiopulmonary Bypass
Sponsor
Hospices Civils de Lyon
Enrollment
40
Locations
1
Primary Endpoint
Measurement of femoral, radial and humeral pulses during a cardiopulmonary by-pass (CPBP).
Status
Completed
Last Updated
7 months ago

Overview

Brief Summary

Central and peripheral arterial pressure decoupling occurs in some clinical conditions like sepsis or cardiopulmonary bypass. This decoupling may leed to unsuitable decisions such as the use of catecholamines.

The aim of this study is to evaluate the pulse wave's speed as a marker of central and peripheral arterial pressure decoupling in a scheduled condition which is the cardiopulmonary bypass during cardiac surgery.

Registry
clinicaltrials.gov
Start Date
January 1, 2016
End Date
September 1, 2016
Last Updated
7 months ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Scheduled patient for coronary or valvular surgery with cardiopulmonary bypass
  • Cardiopulmonary bypass is at least 90 minutes
  • Written consent is needed

Exclusion Criteria

  • Patient with heart rate disorder
  • Patient with aortic dissection
  • Dobutamine/milrinone/levosimendan treatment before surgery
  • Patient with heart rate due to a pacemaker

Outcomes

Primary Outcomes

Measurement of femoral, radial and humeral pulses during a cardiopulmonary by-pass (CPBP).

Time Frame: Day one (6 times)

Pulse wave's speed is calculated using 1) time between ECG R-wave and local detection of the pulse wave (femoral, humeral and radial) 2) a length from heart to these sites. Wave detection at femoral and humeral sites will use oscillometry and wave detection at radial site will use an invasive catheter which is always set for this surgery.

Study Sites (1)

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