Central and Peripheral Arterial Pressure Decoupling In Cardio-Pulmonary Bypass
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Measurement of femoral, radial and humeral pulses during a cardiopulmonary by-pass (CPBP).
研究概览
简要总结
Central and peripheral arterial pressure decoupling occurs in some clinical conditions like sepsis or cardiopulmonary bypass. This decoupling may leed to unsuitable decisions such as the use of catecholamines.
The aim of this study is to evaluate the pulse wave's speed as a marker of central and peripheral arterial pressure decoupling in a scheduled condition which is the cardiopulmonary bypass during cardiac surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Scheduled patient for coronary or valvular surgery with cardiopulmonary bypass
- •Cardiopulmonary bypass is at least 90 minutes
- •Written consent is needed
排除标准
- •Patient with heart rate disorder
- •Patient with aortic dissection
- •Dobutamine/milrinone/levosimendan treatment before surgery
- •Patient with heart rate due to a pacemaker
研究组 & 干预措施
Pulse wave's speed observational arm
Whole patients for who the pulse wave's speed are measured during a cardiopulmonary bypass during cardiac surgery
干预措施: Non-invasive blood pressure oscillometer (NIBP) implementation (Procedure)
结局指标
主要结局
Measurement of femoral, radial and humeral pulses during a cardiopulmonary by-pass (CPBP).
时间窗: Day one (6 times)
Pulse wave's speed is calculated using 1) time between ECG R-wave and local detection of the pulse wave (femoral, humeral and radial) 2) a length from heart to these sites. Wave detection at femoral and humeral sites will use oscillometry and wave detection at radial site will use an invasive catheter which is always set for this surgery.
次要结局
未报告次要终点