Effects of Ten-Weeks Resistance Training on Neuromuscular Performance, Heart Rate Variability, Sleep Quality and Mobility in Persons With Multiple Sclerosis
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Multiple Sclerosis
- Sponsor
- Universidad Católica San Antonio de Murcia
- Enrollment
- 36
- Locations
- 1
- Primary Endpoint
- Spasticity
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
Multiple Sclerosis (ME) is a degenerative, inflammatory and autoimmune demyelinating disease of the central nervous system, characterized by demyelination due to inflammation and degeneration of the myelin sheaths enveloping nerves of the eye, periventricular grey matter, brain, spinal cord and brainstem. The symptoms associated with MS include symptomatic fatigue, muscle weakness, ataxia, mobility and balance problems or cognitive problems. Strength training has been shown to improve strength and mobility in persons with MS.
Investigators
Jacobo Á. Rubio
Principal Investigator
Universidad Católica San Antonio de Murcia
Eligibility Criteria
Inclusion Criteria
- •mild or moderate disability with clinical mild spastic-ataxic gait disorder.
- •stable phase of the disease.
Exclusion Criteria
- •Expanded Disability Status Scale (EDSS) \<
- •relapsing disease within the preceding 12 months.
- •corticosteroid treatment within the last months before study inclusion.
Outcomes
Primary Outcomes
Spasticity
Time Frame: After 10 weeks
Pendulum test
Maximal Voluntary Isometric Contraction of Knee Extension
Time Frame: After 10 weeks
Rate of Force Development
Time Frame: After 10 weeks
Central Activation Ratio
Time Frame: After 10 weeks
Secondary Outcomes
- Walking speed(After 10 weeks)
- Static balance(After 10 weeks)
- Functional capacity(After 10 weeks)
- Heart Rate Variability(After 10 weeks)
- Sleep Quality(After 10 weeks)