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Clinical Trials/CTRI/2017/10/010174
CTRI/2017/10/010174
Completed
未知

Effect of Leucocyte platelet rich fibrin on healing of medicine induced osteonecrosis of jaw- pilot study

Tata Memorial Centre0 sites15 target enrollmentTBD
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ConditionsHealth Condition 1: C00-D49- NeoplasmsHealth Condition 2: null- Patients who have developed medicine related osteonecrosis of jaw (MRONJ) lesions due to antiresorptive drugs like Bisphophonates

Overview

Phase
未知
Intervention
Not specified
Conditions
Health Condition 1: C00-D49- NeoplasmsHealth Condition 2: null- Patients who have developed medicine related osteonecrosis of jaw (MRONJ) lesions due to antiresorptive drugs like Bisphophonates
Sponsor
Tata Memorial Centre
Enrollment
15
Status
Completed
Last Updated
2 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
March 30, 2020
Last Updated
2 years ago
Study Type
Interventional

Investigators

Eligibility Criteria

Inclusion Criteria

  • •1\)Patients who are on, or who have had, treatment with antiresorptives or antiangiogenic agents i.e. Zoledronate, Alodronate, Pamidronate, Ibandronate, Denosumab, Sunitinib, Sorafenib, Bevacizumab and who have necrosis of jaw bone (ONJ)
  • •2\)Patients with ONJ sites that had failed to heal for 8 weeks or longer despite continuous treatment with antimicrobial drugs
  • •3\)Age \> 18 years

Exclusion Criteria

  • •1\.Patients who have been given radiotherapy to head neck region
  • •2\.Patients who have neoplastic involvement of the jaw.
  • •3\.Patients in whom MRONJ extends till lower border of mandible / sinus floor / zygoma requiring major ostectomies for debridement of necrosed bone

Outcomes

Primary Outcomes

Not specified

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