Prevention of neonatal hypoglycemias with oral dextrose gel among high-risk neonates admitted in Tertiary care centre
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- prevention of hypoglycemia among high risk neonates
Study Overview
Brief Summary
Glucose is the principal substrate for cerebral metabolism, and neonatal hypoglycemia causes damage in neuroglial cells and leads to adverse neurodevelopmental outcome.Approximately 25% of neonates are at risk for neonatal hypoglycemia. Some of these infants fail to normalize blood glucose levels by feed alone and require intravenous dextrose therapy. Preterm infants, small for gestational age (SGA), large for gestational age (LGA), infants of diabetic mothers are at high risk of requiring intravenous dextrose therapy due to persistent hypoglycemia.
In this study, we aim to study about the use of oral dextrose gel (40%) in preventing hypoglycemia in at risk neonates which helps in better neurodevelopmental outcome and the use of oral dextrose gel in preventing hospital admission and early initiation of breastfeeding
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Masking
- None
Eligibility Criteria
- Ages
- 0.00 Day(s) to 7.00 Day(s) (—)
- Sex
- All
Inclusion Criteria
- •preterm, small for gestational age, large for gestational age, infants of diabetic mothers.
Exclusion Criteria
- •sepsis, endocrine causes.
Outcomes
Primary Outcomes
prevention of hypoglycemia among high risk neonates
Time Frame: every 6th hourly for 72 hours of life
Secondary Outcomes
- EARLY DISCHARGE RATE(1 week)
Investigators
DrUthayashree P
Gulbarga institute of medical sciences