Blood Flow Index as an Indicator of Successful Peripheral Nerve Block : A Prospective Observational Study Using Laser Speckle Contrast Imaging.
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Laser
- Sponsor
- Huazhong University of Science and Technology
- Enrollment
- 110
- Locations
- 1
- Primary Endpoint
- diagnostic power of LSCI and pinprick sensory tests for predicting successful and failed blocks
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
Laser speckle contrast imaging (LSCI) allows real-time, non-invasive, quantitative measurements of regional blood flow. The aim of this prospective observational study was to evaluate the blood flow changes by LSCI after peripheral nerve block and determine whether this novel optical technique can be used as a reliable indicator of successful blocks.
Detailed Description
Methods: One hundred adult patients scheduled for elective upper or lower limb surgery with peripheral nerve block will receive LSCI measurements and pinprick sensory tests before the block and at 5-min intervals till 30 min after the block. The sensitivity, specificity of LSCI as a diagnostic method will be determined by receiver operator characteristic analysis. Clinical Implications: LSCI with quantitative data could be used as an indicator of successful blocks.
Investigators
Wei Mei
Vice Director, Department of Anaesthesiology, Tongji Hospital of Tongji Medical College
Huazhong University of Science and Technology
Eligibility Criteria
Inclusion Criteria
- •informed consent
- •American Society of Anesthesiologists physical statusⅠ-Ⅱ
- •Undergo elective upper or lower limb surgery with peripheral nerve block
Exclusion Criteria
- •refusal to participate in the study
- •peripheral vascular disease
- •digit injury or deficiency
- •colored or infected fingernails/toenails
- •those who had taken vasodilatory drugs before surgery
- •preoperative analgesic medications
- •Any contraindications to peripheral nerve block such as coagulation abnormalities, allergy to local anaesthetics, peripheral neuropathy.
Outcomes
Primary Outcomes
diagnostic power of LSCI and pinprick sensory tests for predicting successful and failed blocks
Time Frame: at 5-min intervals till 30 min after regional block
sensitivity and specificity
Secondary Outcomes
- blood flow index(5 min before regional block and at 5-min intervals till 30 min after regional block)