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临床试验/NCT05876637
NCT05876637已完成不适用

Effects of Left Nostril Breathing in Young Females Having Cardiovascular Hyper Reactivity to Cold Pressor Test.

Riphah International University2 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2023年9月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
60
试验地点
2
主要终点
Cold pressor test

研究概览

简要总结

The purpose of this study is to evaluate the effects of left nostril breathing in young females having cardiovascular hyper reactivity to cold pressor test.Although,limited literature exist regarding hyper reactivity towards stress induced test in our youth and its effective and easy treatment in the form of left nostril breathing which could proves to be beneficial for our youth.

详细描述

The Cold Pressor Test (CPT) was introduced as a standard incentive for studying the vasomotor response (Hines and Brown 1932). Hyper-reactors were the subjects in his study who responded more strongly to CPT, Participants who show hyper reactivity to Cold pressor test (i.e. subjects showing 25 mmHg increase in systolic blood pressure along with 20 mmHg increase in diastolic blood pressure).They proposed that these hyper reactive could be candidates for hypertension in the future. Increased occurrence of these diseases could be attributed to an asymmetry in sympathetic and parasympathetic stimulation. Control or adaptation of breathing or breathing workouts i-e yoga are thought to be beneficial in the treatment of such disease. Although Yoga techniques proven to be effective in treating stress related disorders but it is time consuming and young population because of their busy routine couldn't be able to take out time for their health related issues. This study introduces very simple exercise in the form of left nostril breathing which decreases sympathetic activity and increases parasympathetic activity. It is inversely proportional to stress induced response of the body, it is very easy to perform and can be done at any time, and if found significantly effective for stress disorder ,it could be used in daily routine by our youth to get themselves prevented from major risk factors of CVD's particularly hypertension. This study will identify participants with a high potential risk of developing hypertension in the future by administering Cold pressor test, additionally the effects of left nostril breathing intervention on hyper reactive participants would be observed and if found significant, it would be a major breakthrough in primary prevention of hypertension.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Other
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
18 Years 至 25 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • Participants falling in the following category would be recruited into the study:
  • Females Age (18-25) years
  • Participants who show hyper reactivity to Cold pressor test (i.e subjects showing 25mmHg increase in systolic blood pressure along with 20mmHg increase in diastolic blood pressure)
  • Consenting participants.

排除标准

  • The participants in the following category would be excluded from the study:
  • Participants on antihypertensive drugs.
  • Participants who are diagnosed with any cardiovascular, renal, hepatic or metabolic disease.
  • Participants having malignant tumor.
  • Participants with nasal blockages, polyps ,Raynaud phenomena
  • Females during menstrual cycle, pregnancy or on oral contraceptives.

结局指标

主要结局

Cold pressor test

时间窗: After 4 weeks

Cold pressor test will be conducted on participants to measure cardio vascular hyper reactivity to stress induce test.

Blood pressure

时间窗: After 4 weeks

Mercury sphygmomanometer will be used to measure blood pressure of participants

Heart Rate

时间窗: After 4 weeks

Pulse oximeter will be applied to the participant to measure their Heart rate.

次要结局

  • Oxygen saturation(after 4 weeks)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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