Comparison of GFR measurement and GFR estimation with 125I-labelled iothalamate, 51Cr-EDTA, Gd DTPA, and two formulas based on cystatin C and creatinine.
- Conditions
- kidney diseaserenal failure10029149
- Registration Number
- NL-OMON31536
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
- > 18 years
-Patients have to belong to one of the following categories: those with Fabry disease, those with HIV, those with a status after renal transplantation or those that are willing to donate a kidney.
-Patients (from the outpatient clinic of metabolic diseases and infectious diseases) in whom renal function was measured with 125I-labeled iothalamate/131I-labeled hippuran GFR in the previous year (i.e patients with Fabry disease or with HIV).
-Stable renal function as estimated by a stable serum creatinine during the previous year.
Exclusion Criteria
-Female patients who are pregnant or unwilling to use adequate contraception during the study.
-A known allergy to either 51Cr-EDTA or gadolineum DTPA (Magnevist).
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method