Clinical effectiveness of a synbiotic

Not Applicable

Completed

• Conditions: Metabolic syndrome; Nutritional, Metabolic, Endocrine

• Registration Number: ISRCTN37346212
• Lead Sponsor: Committee of Science of the Ministry of Science and Education of the Republic of Kazakhstan

Brief Summary

2020 gut microbial analysis results in https://pubmed.ncbi.nlm.nih.gov/30056386/ (added 25/11/2020)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2015-01-31
• Study Start: 2017-10-18
• Last Update Posted: 7 December 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 180

Inclusion Criteria

1. No history of the use of probiotics or antibiotics for 3 months
2. Blood pressure: = 130/90 mmHg
3. Raised fasting plasma glucose (FPG): >100 mg/dL (5.6 mmol/L), or previously diagnosed type 2 diabetes
4. Dyslipidemia TG: = 1.695 mmol/L; HDL-C = 0.9 mmol/L (male), = 1.0 mmol/L (female)
5. Central obesity: waist:hip ratio > 0.90 (male); > 0.85 (female), or body mass index > 30 kg/m2

Exclusion Criteria

1. Acute illness or fever at the time of recruitment
2. Positive for HIV, hepatitis B or C, or for human papillomavirus (HPV)
3. Had anamnesis for surgery of the gastrointestinal tract, including any bowel resection
4. Pregnant or breastfeeding
5. Participants who had used the following medications during the last 6 months: antibiotics, antifungal, antiviral or antiparasitic drugs; corticosteroids; cytokines; commercial probiotics; or vaccines

Study & Design

• Study Type: Interventional
• Study Design: Not specified