TCTR20190128001招募中1 期
Effects of oral coenzyme Q10 supplementation and ischemic preconditioning on tourniquet-induced ischemia and reperfusion injury in unilateral total knee arthroplasty
/A0 个研究点目标入组 60 人开始时间: 2019年1月28日最近更新:
适应症
试验速览
- 阶段
- 1 期
- 状态
- 招募中
- 发起方
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 60 Years 至 80 Years（—）
- 性别
- All
入选标准
- •Osteoarthritis of knee joint patients with ASA classification I-III who are scheduled for elective unilateral total knee arthoplasty
排除标准
- •1. Body mass index ≤ 35 kg/m2
- •2. Presentation of any conditions that may interfere the oxidative stress levels including any malignant diseases, any infectious diseases, neurodegenerative diseases, atherosclerotic disease, peripheral arterial disease, chronic kidney disease and active heavy smoking
- •3. Antioxidant use within 4 weeks
- •4. Glucocorticoid use within 3 months
- •5. Presentation of contraindications of regional anesthesia including coagulopathy and increased intracranial pressure
- •6. Allergy to any medications in the study protocol
- •7. Presentation of any conditions that may interfere clinical assessment including preoperative immobility, preoperative delirium or cognitive dysfunction
- •8. Perioperative blood transfusion
研究者
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