Multi center randomized controlled clinical trial of Xiezhuo Tongluo Formula in the treatment of chronic kidney disease stage 3-4
Phase 1
- Conditions
- chronic kidney disease
- Registration Number
- ITMCTR2000003976
- Lead Sponsor
- The First Affiliated Hospital of Guangzhou University of Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
(1) It met the diagnostic criteria of CKD3-4
(2) Aged 18 to 75 years old and can sign the informed consent form independently
(3) Blood pressure 100-160/60-100mmHg.
Exclusion Criteria
(1) Prepare for renal replacement therapy;
(2) Immunosuppressive therapy were performed;
(3) Patients with acute infection, serious primary diseases of heart, lung, brain, liver and hematopoietic system, diabetic ketoacidosis, malignant tumor, active tuberculosis and psychotic patients;
(4) eGFR fluctuated more than 30% in three months;
(5) Severe hyperkalemia (blood potassium>6.5mmol/L);
(6) Allergy history to some components of the drug used;
(7) Pregnant or during lactation;
(8) Participated in other clinical studies.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method eGFR;
- Secondary Outcome Measures
Name Time Method Quality of life assessment;ACR;