Sprint Interval Training to Target Brain Oscillations in Psychosis
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- Change in Individual Alpha Frequency
研究概览
简要总结
Previous studies have shown that cardiorespiratory fitness (how well the heart and lungs are able to function during physical activity) is often reduced in people with psychosis. The goal of this research study is to test the hypothesis that aerobic exercise can lead to small changes in brain functioning that can influence visual perception and attention in psychosis. The type of aerobic exercise used in this study is called Sprint Interval Training, or "SIT". Information from this study will help to develop interventions that enhance cognition and maximize the quality of life for persons living with psychosis.
The exercise procedure used is called SIT, which involves training rigorously on a stationary bike for a short period of time followed by a resting period.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Crossover
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 64 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Meet diagnostic criteria for schizophrenia or schizoaffective disorder
- •Are age 18-64
- •Fluent in written and spoken English
- •Have an outpatient status of at least 1 month prior to participation
- •Has been on a stable dose of psychiatric medication for at least one month prior to participation (titration to a lower dose of psychotropic medications under supervision of a psychiatrist can be allowed at the discretion of the investigators)
排除标准
- •Current or possibility of current pregnancy (self-reported)
- •Active suicidal ideation at screening or baseline assessments, or previous intent to act on suicidal ideation with a specific plan, preparatory acts, or an actual suicide attempt within the last 3 months, as indicated by the C-SSRS
- •WTAR standardized score below 70
- •American College of Sports Medicine contraindication to exercise
结局指标
主要结局
Change in Individual Alpha Frequency
时间窗: through study completion, on average 2 weeks
A prominent neural oscillatory rhythm measured from resting EEG.
Change in Visual Attention
时间窗: through study completion, on average 2 weeks
Computerized tasks that measure speeded sustained attention.
Change in Visual Perception
时间窗: through study completion, on average 2 weeks
Computerized tasks that measure speeded visual perception
次要结局
未报告次要终点