Clinical and genetic analysis of patients with primary failure of eruption (PFE) and their relatives

CharitéCentrum für Zahn-, Mund- und Kieferheilkunde CC 30 个研究点目标入组 30 人开始时间: 2022年3月4日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•The patient must be at least 12 years of age, as an asymmetric eruption of the first permanent molars becomes evident (to avoid premature (incorrect) diagnosis of the eruption disorder). Gender does not matter, but must be specified for the evaluation of the genetic analysis.
•The number of study participants:
•Spirit. 10 trios with PFE (affected children of two phenotypically healthy or affected parents or affected family members)

•Absence of an impacted tooth in the pretherapeutic orthopantomogram (root growth of the teeth that have not yet erupted is not complete).
•Abnormal tooth germ position, tooth germ malformation, bone deficit in patients with clefts, dilaceration.
•Syndromic and systemic diseases
•Teeth that do not erupt due to lack of space.

发起方

CharitéCentrum für Zahn-, Mund- und Kieferheilkunde CC 3