A prospective clinical registry study of genetic profiling and targeted therapies in patients with rare hematologic malignancies; MASTER KEY HEM Protocol
Not Applicable
Recruiting
- Conditions
- Rare hematologic malignancies
- Registration Number
- JPRN-UMIN000036756
- Lead Sponsor
- ational Cancer Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 500
Inclusion Criteria
Not provided
Exclusion Criteria
1. Patients with complications of psychiatric disorders/symptoms that interfere daily life are considered to hamper their participation in the study.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1) Overall incidence of genetic abnormality 2) Incidence of individual genetic abnormalities 3) Biomarker-positive rate 4) Number of somatic mutations and distribution of mutation rate within exons 5) Response rate 6) Disease control rate 7) Overall survival 8) Progression-free survival
- Secondary Outcome Measures
Name Time Method